Mlb Opening Day 2025 Schedule Dates. Major league baseball today announced its preliminary schedule for the 2025 season, with the dodgers opening the campaign in asia for the second straight year, this time in tokyo, japan on march 18 and march 19 vs. The 15 games on traditional opening day will feature four divisional matchups and five interleague contests.

Major league baseball announced the 2025 schedule thursday with a number of key dates to keep an eye on. Please see the accompanying files or visit mlb.com for the complete.